BDBM50383138 CHEMBL2031762

SMILES C[C@@H]1CCCN1CCN1CCc2cc(ccc2C1=O)-c1ccc(cc1)C#N

InChI Key InChIKey=TXFFWCPTQAOPNJ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383138   

TargetHistamine H3 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383138(CHEMBL2031762)
Affinity DataKi:  0.800nMAssay Description:Displacement of [3H]-(R)-alpha-methylhistamine from human H3 receptor expressed in HEK293T cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50383138(CHEMBL2031762)
Affinity DataKi:  5.80nMAssay Description:Displacement of [3H]-(R)-alpha-methylhistamine from rat H3 receptor expressed in HEK293T cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50383138(CHEMBL2031762)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ERG by IonWorks assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed