BDBM50383657 CHEMBL2029846

SMILES Clc1ccc(cc1)C1=NC(=O)\C(S1)=C\c1cccc(Oc2ccccc2)c1

InChI Key InChIKey=VMXJEYKZNVUTKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50383657   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383657(CHEMBL2029846)
Affinity DataIC50: 90nMAssay Description:Inhibition of 5-lipoxygenase in cell free S100 freshly isolated human PMNL cells assessed as inhibition of A23187-stimulated 5-LO product formation p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Zafes/Liff/Osf Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50383657(CHEMBL2029846)
Affinity DataIC50: 320nMAssay Description:Inhibition of 5-lipoxygenase in human polynuclear leukocytes assessed as inhibition of A23187-stimulated 5-LO product formation preincubated for 15 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed