BDBM50383772 CHEMBL451812

SMILES COC(OC)C1=C(C(C(C(O)=O)C(C)=N1)c1cccc(Cl)c1)C(=O)OC\C=C\c1ccccc1

InChI Key InChIKey=LIQVEBDPZWRFSM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50383772   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-type voltage-dependent calcium channel CaV2.2 in human IMR32 cells assessed as inhibition of KCl-induced increase in intracellular ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in rat thoracic aorta ring assessed as effect on high K+ induced contraction by Magnus methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rat)
Ajinomoto Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50383772(CHEMBL451812)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of Voltage-dependent L-type calcium channel in rat thoracic aorta ringMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed