BDBM50383854 CHEMBL2031148

SMILES CC(=O)N[C@@H](Cc1ccc(F)cc1)[C@H](O)CN[C@H]1C[C@]2(C[C@H](O)C2)Oc2ncc(CC(C)(C)C)cc12

InChI Key InChIKey=WRMXZVCISFLWNB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383854   

TargetBeta-secretase 1(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383854(CHEMBL2031148)
Affinity DataIC50: 3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383854(CHEMBL2031148)
Affinity DataIC50: 5nMAssay Description:Inhibition of BACE1 in human HEK293 cells stably expressing APPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383854(CHEMBL2031148)
Affinity DataIC50: 577nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed