BDBM50383856 CHEMBL2031150

SMILES CC(C)(C)Cc1cnc2O[C@@]3(C[C@H](O)C3)C[C@H](NC[C@@H](O)[C@H](Cc3ccc(F)cc3)NC(=O)CF)c2c1

InChI Key InChIKey=QDNYUOBQNJAFJZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50383856   

TargetBeta-secretase 1(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383856(CHEMBL2031150)
Affinity DataIC50: 4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383856(CHEMBL2031150)
Affinity DataIC50: 10nMAssay Description:Inhibition of BACE1 in human HEK293 cells stably expressing APPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
Envoy Therapeutics

Curated by ChEMBL
LigandPNGBDBM50383856(CHEMBL2031150)
Affinity DataIC50: 347nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed