BDBM50384314 CHEMBL2030849

SMILES CCCCc1c(c(nn1-c1cccc(Oc2ccccc2)c1)C(=O)OCC)-c1ccc(cc1C(=O)N1CCc2ccccc2C1)C(=O)NS(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=HJGNMXGROPZMKN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384314   

TargetApoptosis regulator Bcl-2(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384314(CHEMBL2030849)
Affinity DataIC50: 140nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384314(CHEMBL2030849)
Affinity DataIC50: 470nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed