BDBM50384328 CHEMBL2030863

SMILES CCCCCS(=O)(=O)NC(=O)c1ccc(-c2c(CO)nn(c2CCCC)-c2ccc(Oc3cccc(Cl)c3)cc2)c(c1)C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=AYZJLANKCMLFJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384328   

TargetApoptosis regulator Bcl-2(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384328(CHEMBL2030863)
Affinity DataIC50: 65nMAssay Description:Inhibition of GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Bristol-Myers Squibb Research

Curated by ChEMBL
LigandPNGBDBM50384328(CHEMBL2030863)
Affinity DataIC50: 120nMAssay Description:Inhibition of biotin-labelled Bcl-xL using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed