BDBM50384878 CHEMBL2035184

SMILES C(CN1CCCC1)Oc1ccc2Nc3nccc(n3)-c3csc(COC\C=C\COCc1c2)c3

InChI Key InChIKey=HJLQTCJLJAJRFH-ONEGZZNKSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50384878   

TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of recombinant CDK2 using RbING as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  47nMAssay Description:Inhibition of TYK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  680nMAssay Description:Inhibition of recombinant JAK3 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant JAK1 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant JAK2 using poly(Glu,Ala,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50384878(CHEMBL2035184)
Affinity DataIC50:  45nMAssay Description:Inhibition of recombinant FLT3 using poly(Glu,Tyr) as substrate after 2 hrs by luminometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed