BDBM50384902 CHEMBL2036276

SMILES CCN[C@H]1CCC[C@H](c2c[nH]c3ccc(N=C(N)c4cccs4)cc23)C1

InChI Key InChIKey=RDNPSSHSVPTCKN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50384902   

TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384902BDBM50384902(CHEMBL2036276)
Affinity DataIC50: 200nMAssay Description:Inhibition of human nNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Neuraxon

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384902BDBM50384902(CHEMBL2036276)
Affinity DataIC50: 760nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384902BDBM50384902(CHEMBL2036276)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384902BDBM50384902(CHEMBL2036276)
Affinity DataIC50: 5.42E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus-infected insect sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrulline preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed