BDBM50385457 CHEMBL2036774

SMILES Clc1ccc(NC(=O)N2CCN(C[C@H]3CN(CCO3)C3CC3)CC2)cc1Cl

InChI Key InChIKey=IXACLKNSEGSKGF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385457   

TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385457(CHEMBL2036774)
Affinity DataIC50: 262nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385457(CHEMBL2036774)
Affinity DataIC50: 267nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50385457(CHEMBL2036774)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed