BDBM50385458 CHEMBL2036773

SMILES CCN1CCO[C@@H](CN2CCN(CC2)C(=O)Nc2ccc(Cl)c(Cl)c2)C1

InChI Key InChIKey=GRFCHFVLEURDEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385458   

TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385458(CHEMBL2036773)
Affinity DataIC50: 64nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385458(CHEMBL2036773)
Affinity DataIC50: 277nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50385458(CHEMBL2036773)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed