BDBM50385464 CHEMBL2036762

SMILES Cc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(C3)C3CC3)CC2)cc1Cl

InChI Key InChIKey=UYGVZNATVIIKQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50385464   

TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385464(CHEMBL2036762)
Affinity DataIC50: 27nMAssay Description:Displacement of 125I-MCP1 from human CCR2 receptor expressed in human THP-1 cell membrane by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50385464(CHEMBL2036762)
Affinity DataIC50: 184nMAssay Description:Antagonist activity at human CCR2 receptor expressed in human THP-1 cells assessed as inhibition of MCP1-induced Ca2+ flux by FLIPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50385464(CHEMBL2036762)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed