BDBM50385809 CHEMBL2043007

SMILES Cc1cccnc1CN1CCC2(CC1)N(C(=O)N(C2=O)c1ccc(cc1)-c1ccccc1)c1ccnc(=O)[nH]1

InChI Key InChIKey=XEBIKXNLTIXWSW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50385809   

TargetProlyl hydroxylase EGLN2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385809(CHEMBL2043007)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PHD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385809(CHEMBL2043007)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385809(CHEMBL2043007)
Affinity DataIC50: 44nMAssay Description:Inhibition of PHD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385809(CHEMBL2043007)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385809(CHEMBL2043007)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed