BDBM50385832 CHEMBL2043004

SMILES Cc1cccnc1CN1CCC2(CC1)N(C(=O)N(C2=O)c1ccc(cc1)-c1ccccc1)c1cc(=O)[nH]cn1

InChI Key InChIKey=SGDWPIDXMHBDQC-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50385832   

TargetProlyl hydroxylase EGLN2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PHD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of FLAG-tagged PHD2 expressed in baculovirus infected insect sf9 cells using biotinyl-DLDLEMLAPYIPMDDDFQL as substrate preincubated with c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProlyl hydroxylase EGLN3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 11nMAssay Description:Inhibition of PHD3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 220nMAssay Description:Binding affinity to human ErgMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cav1.2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PXRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50385832(CHEMBL2043004)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed