BDBM50386053 CHEMBL2042769

SMILES CN(Cc1ccc(CNS(C)(=O)=O)cc1)C(=O)c1cc2c(Cc3cccc(C)c3)n[nH]c2cc1O

InChI Key InChIKey=MYLPKVZOKNWTDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386053   

TargetHeat shock protein HSP 90-beta(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50386053(CHEMBL2042769)
Affinity DataIC50: 150nMAssay Description:Displacement of [3H]17AAG from human recombinant Hsp90 after 30 mins by beta scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-beta(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50386053(CHEMBL2042769)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Hsp90 in human A2780 cells assessed as Hsp70 upregulation after 24 hrs by immunostaining methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed