BDBM50386746 CHEMBL2046478

SMILES CCCc1nc2ccc(NC(=O)c3ccccc3Cl)cc2c(=O)n1Cc1ccc(cc1)-c1cccc(OC)c1

InChI Key InChIKey=MJNUQNOAEWRZCF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50386746   

TargetProstaglandin E synthase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50386746(CHEMBL2046478)
Affinity DataIC50: 210nMAssay Description:Inhibition of mPGES-1 derived from IL1beta and TNFalpha stimulated human HeLa cells microsomal fraction using PGH2 as substrate preincubated for 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed