BDBM50386758 CHEMBL2046893

SMILES Fc1ccc(cc1)N(CCNCCCc1ccccc1)c1ccc(F)cc1

InChI Key InChIKey=KCVDLYFIRMHDBH-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50386758   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50386758(CHEMBL2046893)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50386758(CHEMBL2046893)
Affinity DataIC50: 2.51nMAssay Description:Inhibition of human ERG expressed in HEK cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPteridine reductase 1(Leishmania major)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50386758(CHEMBL2046893)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetPteridine reductase 1(Leishmania major)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50386758(CHEMBL2046893)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed