BDBM50386950 CHEMBL2048815

SMILES CCCOc1ccc(CN2CC3(C2)CCN(CC3)C(=O)Cc2ccc(OC)cc2)cn1

InChI Key InChIKey=JVLMJTHFAZVCKD-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50386950   

TargetGrowth hormone secretagogue receptor type 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50386950(CHEMBL2048815)Copy SMILESCopy InChI

Affinity DataKi:  114nMAssay Description:Antagonist activity at human GHS-R1a expressed in HEK293 cells assessed as inhibition of ghrelin-induced europium-labeled GTP binding by DELFIAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetGrowth hormone secretagogue receptor type 1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50386950(CHEMBL2048815)Copy SMILESCopy InChI

Affinity DataIC50: 407nMAssay Description:Displacement of [125I]Ghrelin from human GHS-R1a expressed in HEK293 cells after 8 hrs by SPAMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/7/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL