BDBM50387308 CHEMBL2048866

SMILES N[C@@H]1CCCN(C1)c1c(Cl)cccc1C=C1SC(O)=NC1=O

InChI Key InChIKey=ZLDXTUTZYPVCKG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50387308   

TargetSerine/threonine-protein kinase pim-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387308(CHEMBL2048866)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 50 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387308(CHEMBL2048866)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PIM1 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387308(CHEMBL2048866)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PIM3 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50387308(CHEMBL2048866)
Affinity DataIC50: 310nMAssay Description:Inhibition of human PIM2 using FITC-(AHX)RSRHSSYPAGT-COOH as substrate after 90 mins by mobility shift assay in presence of 5 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387308(CHEMBL2048866)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed