BDBM50387318 CHEMBL2046623

SMILES CC(C)N(C(=O)\C=C\c1ccccc1)c1cccc(CN2CCc3nc(sc3C2)C(=O)NO)c1

InChI Key InChIKey=RXIWHWGDUAVETL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50387318   

TargetHistone deacetylase 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387318(CHEMBL2046623)
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC6 expressed in insect High5 cells using Boc-Lys(eacetyl)- AMC as substrate after 3 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387318(CHEMBL2046623)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC3 expressed in insect High5 cells using Ac-Lys-Tyr-Lys(e-acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50387318(CHEMBL2046623)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of human recombinant His6-tagged and GST-fuses HDAC1 expressed in insect High5 cells using Ac-Lys-Tyr-Lys(e-acetyl)-AMC as substrate after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed