BDBM50387546 CHEMBL2057363

SMILES CN(C)C(=O)CNC(=O)Nc1nc2ccc(cn2n1)-c1cncc(c1)S(=O)(=O)NC(C)(C)C

InChI Key InChIKey=RXGDQEJCSZROIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50387546   

LigandPNGBDBM50387546(CHEMBL2057363)
Affinity DataIC50: 3.16nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387546(CHEMBL2057363)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387546(CHEMBL2057363)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PI3Kbeta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387546(CHEMBL2057363)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of PI3Kalpha in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed