BDBM50387887 CHEMBL2057798

SMILES CCN1CCN(CC1)c1nc(C)nc2n(C)c(nc12)-c1ccccc1Cl

InChI Key InChIKey=UMDBIKLFXMBCMH-UHFFFAOYSA-N

Data  3 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50387887   

TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma binding after 30 mins by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataKi:  8.20nMAssay Description:Displacement of [3H]-CP-55940 from rat CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataKi:  8.60nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataEC50:  948nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells assessed as stimulation of [35S]GTPgamma binding incubated for 15 mins prior to [35S]GT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataEC50:  948nMAssay Description:Agonist activity at human CB1 receptor expressed in CHO cells assessed as [35S]-GTPgammaS binding preincubated for 25 mins measured after 30 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50387887(CHEMBL2057798)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed