BDBM50388741 CHEMBL2058864

SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(=O)NCCc1ccc(OC)c(OC)c1

InChI Key InChIKey=IEUPDMDPHSCKBD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388741   

TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataKd:  1.82nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388741(CHEMBL2058864)
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed