BDBM50388784 CHEMBL2062575

SMILES CN(C)CCCNc1cc(nc2c(cnn12)C#N)-n1ccc2ccc(NC(C)=O)cc12

InChI Key InChIKey=LGAQZKSRZOPELW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50388784   

TargetCasein kinase II subunit alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388784(CHEMBL2062575)
Affinity DataIC50: 30nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50388784(CHEMBL2062575)
Affinity DataIC50: 60nMAssay Description:Inhibition of HipK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388784(CHEMBL2062575)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CK2alpha in human HCT116 cells assessed as decrease in AKT phosphorylation at S129 residue after 3 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388784(CHEMBL2062575)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388784(CHEMBL2062575)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed