BDBM50388897 CHEMBL2063250::US20240189287, Com. 10Q (ref)

SMILES CS(=O)(=O)CC(=O)NC1CCCOc2c1nn(c2-c1ccc(Cl)cc1)-c1ccccc1Cl

InChI Key InChIKey=DWOBQZTWQMDPBQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50388897   

TargetCannabinoid receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388897(CHEMBL2063250 | US20240189287, Com. 10Q (ref))
Affinity DataKi:  0.540nMAssay Description:Displacement of [3H]SR141716A form human CB1 receptor expressed in HEK293 cells after 60 mins by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388897(CHEMBL2063250 | US20240189287, Com. 10Q (ref))
Affinity DataKi:  0.820nMAssay Description:Antagonist activity at human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of CP-55940-induced [35S]GTPgammaS binding incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Mouse)
Bionanosim (Bns

US Patent
LigandPNGBDBM50388897(CHEMBL2063250 | US20240189287, Com. 10Q (ref))
Affinity DataKi:  111nMAssay Description:Mouse brain membranes were used as the source material for CB1 receptors. The displacement of specifically bound tritiated CP-55.940 from these membr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2024
Entry Details
US Patent

TargetCannabinoid receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388897(CHEMBL2063250 | US20240189287, Com. 10Q (ref))
Affinity DataKi:  5.90E+4nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptor expressed in CHO-K1 cells after 60 mins by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed