BDBM50389221 CHEMBL2063335

SMILES CN1CCN(CC1)c1cc(Nc2cc(n[nH]2)-c2ccc(CNC(=O)OCc3ccccc3)cc2)nc(C)n1

InChI Key InChIKey=HRNJXVNMZJIOTD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389221   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50389221(CHEMBL2063335)
Affinity DataIC50: 18nMAssay Description:Inhibition of wild type FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50389221(CHEMBL2063335)
Affinity DataIC50: 310nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50389221(CHEMBL2063335)
Affinity DataIC50: 420nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase A(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50389221(CHEMBL2063335)
Affinity DataIC50: 430nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed