BDBM50389243 CHEMBL2063456

SMILES Nc1n[nH]c2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(F)c(F)c4)c3)c12

InChI Key InChIKey=OPHBGODQXKELTE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389243   

TargetAurora kinase A(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389243(CHEMBL2063456)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of Aurora A kinase by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389243(CHEMBL2063456)
Affinity DataIC50:  28nMAssay Description:Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed