BDBM50390072 CHEMBL2069427

SMILES COc1cnc(cn1)-c1cccc2OC[C@H](Cc12)NC(=O)c1ccc(COCC(F)(F)F)nc1

InChI Key InChIKey=LRHQXIQLHVPUNA-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50390072   

TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390072BDBM50390072(CHEMBL2069427)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by whole-cell voltage clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390072BDBM50390072(CHEMBL2069427)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50390072BDBM50390072(CHEMBL2069427)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human NaV1.5 expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50390072BDBM50390072(CHEMBL2069427)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed