BDBM50390708 CHEMBL2070317

SMILES Cc1c(c2cccnc2[nH]1)[C@@H]3CCN(C3)C(=O)C4(CC4)c5ccccn5

InChI Key InChIKey=HUWRMRPEILCPLL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50390708   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50390708(CHEMBL2070317)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli assessed as conversion of cortisone to cortisol level after 150 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed