BDBM50390756 CHEMBL2070454

SMILES CC(C)CN(c1ccc(cc1)C(O)(C#Cc1cccc(c1)S(C)(=O)=O)C(F)(F)F)S(=O)(=O)c1cccc(c1)C#N

InChI Key InChIKey=WYHNSMFWOKJJLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390756   

TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390756(CHEMBL2070454)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]N-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-methylbenzenesulfonamide from GST-tagged LXRbeta ligand binding domai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390756(CHEMBL2070454)
Affinity DataIC50: 7.00E+3nMAssay Description:Antagonist activity at LXRbeta ligand binding domain expressed in HEK293 cells coexpressing GAL4 assessed as decrease in [3H]N-(4-(1,1,1,3,3,3-hexafl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed