BDBM50391488 CHEMBL2147225

SMILES COc1ccc(CCNC(=O)c2ccc(OCCC(F)(F)F)nc2)c(c1)-c1cnc(OC)nc1

InChI Key InChIKey=XRYVLNSTGGEKSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391488   

LigandPNGBDBM50391488(CHEMBL2147225)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391488(CHEMBL2147225)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391488(CHEMBL2147225)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed