BDBM50391845 CHEMBL2147040::US9133160, 30

SMILES Cc1ccncc1-c1cccc2n(cnc12)-c1ccncc1

InChI Key InChIKey=PLGGFCHPEADAOI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391845   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
TBA

Curated by ChEMBL

LigandBDBM50391845(CHEMBL2147040 | US9133160, 30)Copy SMILESCopy InChI

Affinity DataIC50: 405nMAssay Description:Inhibition of CYP17 transfected in human HEK2 cells using [3H]pregnenolone as substrate by SPA assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
TBA

Curated by ChEMBL

LigandBDBM50391845(CHEMBL2147040 | US9133160, 30)Copy SMILESCopy InChI

Affinity DataIC50: 405nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 ul prepared from 7.5 ul additions of microsomes (prepared as...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/16/2016
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL