BDBM50391847 CHEMBL2147042::US9133160, 35

SMILES Cc1ccncc1-c1cccc2n(CC#N)cnc12

InChI Key InChIKey=LGIFLSIUYAIIAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391847   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Meyers Squibb

US Patent
LigandPNGBDBM50391847(CHEMBL2147042 | US9133160, 35)
Affinity DataIC50: 330nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 ul prepared from 7.5 ul additions of microsomes (prepared as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Meyers Squibb

US Patent
LigandPNGBDBM50391847(CHEMBL2147042 | US9133160, 35)
Affinity DataIC50: 330nMAssay Description:Inhibition of CYP17 transfected in human HEK2 cells using [3H]pregnenolone as substrate by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed