BDBM50391850 CHEMBL2147045::US9133160, 44

SMILES Nc1ncncc1-c1cccc2n(CC(F)(F)F)cnc12

InChI Key InChIKey=CQUNHUMZSYHQDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391850   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Meyers Squibb

US Patent
LigandPNGBDBM50391850(CHEMBL2147045 | US9133160, 44)
Affinity DataIC50: 674nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 ul prepared from 7.5 ul additions of microsomes (prepared as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2016
Entry Details
US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Meyers Squibb

US Patent
LigandPNGBDBM50391850(CHEMBL2147045 | US9133160, 44)
Affinity DataIC50: 674nMAssay Description:Inhibition of CYP17 transfected in human HEK2 cells using [3H]pregnenolone as substrate by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed