BDBM50391867 CHEMBL2147290

SMILES CC(C)Oc1ccc(cc1)-c1ccccc1C(=O)Nc1ccc2cc(ccc2n1)C(=O)N[C@H](C(=O)N(C)Cc1ccc(F)cc1)c1ccccc1

InChI Key InChIKey=HMTLPJFACYNTHS-KDXMTYKHSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391867   

TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrosomal triglyceride transfer protein large subunit(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50391867(CHEMBL2147290)
Affinity DataIC50:  0.00200nMAssay Description:Inhibition of MTP in human HepG2 cells assessed as unbound drug level causing inhibition of apoB secretion after 40 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed