BDBM50391954 CHEMBL2152262

SMILES COc1ccc(cc1OC)-c1c[nH]c2ncc(cc12)-c1cccc(N)c1

InChI Key InChIKey=JPTMGCYMHIJHRQ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391954   

TargetMast/stem cell growth factor receptor Kit(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391954BDBM50391954(CHEMBL2152262)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391954BDBM50391954(CHEMBL2152262)
Affinity DataKd:  125nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391954BDBM50391954(CHEMBL2152262)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of wild type c-KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391954BDBM50391954(CHEMBL2152262)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed