BDBM50392976 CHEMBL2152376

SMILES Clc1ccc(CNC(=O)C[C@@H]2C\C=C\CCC(=O)N[C@H](Cc3ccccc3)COC2=O)cc1

InChI Key InChIKey=UKWNCRJUNWWVSK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50392976   

TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Smo in mouse C3H10T1/2 cells assessed as inhibition of human Shh-induced cell differentiation after 48 hrs by alkaline phosphatase repo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli-responsive betagalactosidase activity after 30 hrs by B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50392976(CHEMBL2152376)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Smo in mouse Ptch-deficient MEF cells assessed as inhibition of Shh-induced Gli1 transcriptional activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed