BDBM50393302 CHEMBL2140280
SMILES OCCCNc1nc(nnc1-c1ccccc1)-c1ccccn1
InChI Key InChIKey=ZWQHKUKLAHMVNA-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50393302
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 1.05E+4nMAssay Description:Activation of GFP-tagged HIF1alpha expressed in human U2OS cells assessed as HIF1alpha nuclear translocation by high content imaging assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 2.50E+4nMAssay Description:Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubat...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 1.06E+4nMAssay Description:Activation of human HIF1alpha expressed in human U2OS cells assessed as increase in VEGF expression by RT-PCR analysisMore data for this Ligand-Target Pair