BDBM50393306 CHEMBL2152031
SMILES CN1CCN(CC1)c1nc(nnc1-c1ccccc1)-c1ccccn1
InChI Key InChIKey=VGIAVTRUVBILOH-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50393306
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 1.02E+4nMAssay Description:Activation of GFP-tagged HIF1alpha expressed in human U2OS cells assessed as HIF1alpha nuclear translocation by high content imaging assayMore data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 2.19E+4nMAssay Description:Activation of human HIF1alpha expressed in DFX-induced human U2OS cells incubated for 30 mins prior to DFX-induction measured after overnight incubat...More data for this Ligand-Target Pair
TargetHypoxia-inducible factor 1-alpha(Homo sapiens (Human))
The Broad Institute Probe Development Center
Curated by ChEMBL
The Broad Institute Probe Development Center
Curated by ChEMBL
Affinity DataEC50: 8.69E+3nMAssay Description:Activation of human HIF1alpha expressed in human U2OS cells assessed as increase in VEGF expression by RT-PCR analysisMore data for this Ligand-Target Pair