BDBM50393446 CHEMBL2159505

SMILES CS(=O)(=O)c1ccc(NC(=O)c2cc(c(Sc3c(Cl)cncc3Cl)s2)[N+]([O-])=O)cc1

InChI Key InChIKey=GTEDMDSLGCKYMS-UHFFFAOYSA-N

Data  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50393446   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataIC50: 400nMAssay Description:Inhibition of full length human USP7 (1 to 1102 residues) expressed in Escherichia coli BL21 (DE3) using Ubiquitin-AMC as substrate pre-incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataEC50:  400nMAssay Description:Inhibition of recombinant USP7 expressed in Sf9 cells by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataIC50: 400nMAssay Description:Inhibition of USP7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataIC50: 500nMAssay Description:Inhibition of USP47 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataEC50:  500nMAssay Description:Inhibition of USP47 by Ub-CHOP reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of human USP7 using Ub-EKL as substrate by SDS-PAGE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 47(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50393446(CHEMBL2159505)
Affinity DataEC50:  1.18E+4nMAssay Description:Inhibition of human USP47 using Ub-EKL as substrate by SDS-PAGE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed