BDBM50393459 CHEMBL2159688

SMILES OCC[C@H]1OCC[C@]2([C@@H]1COc1c(F)ccc(F)c21)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=OIAYKSYVOPWLJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50393459   

TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393459(CHEMBL2159688)
Affinity DataIC50: 320nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed