BDBM50393767 CHEMBL2159328

SMILES OC(=O)CCNC(=O)c1ccc(Cn2nc(cc2-c2ccc3ccccc3c2)-c2cc(Cl)cc(Cl)c2)cc1

InChI Key InChIKey=ZESAQYDJDZHJFL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393767   

TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393767(CHEMBL2159328)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlucagon receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393767(CHEMBL2159328)
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 3 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGastric inhibitory polypeptide receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50393767(CHEMBL2159328)
Affinity DataIC50: 4.34E+3nMAssay Description:Antagonist activity at human GIPR expressed in CHO cells assessed as inhibition of glucagon-induced cAMP accumulation preincubated for 30 mins prior ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed