BDBM50393880 CHEMBL2158245

SMILES COc1ccc(CSc2ccc3C(=O)NC(=O)c3c2)cc1

InChI Key InChIKey=YSGUUOXLOOVUTJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50393880   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50393880(CHEMBL2158245)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

LigandPNGBDBM50393880(CHEMBL2158245)
Affinity DataKi:  369nMAssay Description:For the A2a receptor binding study, the incubation contained 10 mg of the original tissue weight of the striatal membranes, 4 nM [3H]NECA, 50 nM CPA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50393880(CHEMBL2158245)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAdenosine receptor A1(Rat)
North-West University

LigandPNGBDBM50393880(CHEMBL2158245)
Affinity DataKi:  1.73E+3nMAssay Description:For the A2a receptor binding study, the incubation contained 10 mg of the original tissue weight of the striatal membranes, 4 nM [3H]NECA, 50 nM CPA,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed