BDBM50394119 CHEMBL2158781

SMILES Cc1cc(F)ccc1OC1CCN(CC2CCN(CC2)[C@@H](Cc2ccc(F)cc2)C(O)=O)CC1

InChI Key InChIKey=CWXOTCCLEKNUJY-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394119   

TargetC-C chemokine receptor type 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50394119(CHEMBL2158781)
Affinity DataKi:  12.6nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50394119(CHEMBL2158781)
Affinity DataKi:  158nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394119(CHEMBL2158781)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of 3,7-Bis[2-(4-nitro[3,5-3H]phenyl)ethyl]-3,7-diazabicyclo[3.3.1]nonane from human ERG expressed in HEK cells after 3 hrs by TopCount a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed