BDBM50394131 CHEMBL2158769

SMILES OC(=O)[C@H](Cc1ccccc1C#N)N1CCC(CN2CCC(CC2)Oc2ccc(Cl)c(Cl)c2)CC1

InChI Key InChIKey=WCXUWQZNCRRRDD-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394131   

TargetC-C chemokine receptor type 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50394131(CHEMBL2158769)
Affinity DataKi:  5.01nMAssay Description:Binding affinity to human CCR3 expressed in CHOK1 cells by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50394131(CHEMBL2158769)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394131(CHEMBL2158769)
Affinity DataIC50: 2.51E+4nMAssay Description:Displacement of 3,7-Bis[2-(4-nitro[3,5-3H]phenyl)ethyl]-3,7-diazabicyclo[3.3.1]nonane from human ERG expressed in HEK cells after 3 hrs by TopCount a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed