BDBM50394382 CHEMBL2159805

SMILES Clc1cccc(CN2CCN(CC2)C(=O)n2nnc3ccccc23)c1

InChI Key InChIKey=QQCWAELFGXREHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394382   

TargetMonoglyceride lipase(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50394382(CHEMBL2159805)
Affinity DataIC50: 2nMAssay Description:Inhibition of human MAGL assessed as [3H]-2-OG hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liquid scintil...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50394382(CHEMBL2159805)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant FAAH assessed as [3H]-AEA hydrolysis preincubated for 30 mins before [3H]-2-OG addition measured after 10 mins by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed