BDBM50394414 CHEMBL2158163

SMILES NC(=O)c1ccc(NC(=O)[C@@H](Cc2ccccc2)NC(=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=RODNKZSOMPELAT-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394414   

TargetBile acid receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50394414(CHEMBL2158163)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at FXRalpha expressed in HEK293 cells assessed as increase in transcriptional activity after 18 hrs by luciferase reporter gene assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBile acid receptor(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50394414(CHEMBL2158163)
Affinity DataEC50:  1.29E+4nMAssay Description:Agonist activity at GST-tagged FXRalpha ligand binding domain assessed as biotinylated SRC1 binding after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed