BDBM50394515 CHEMBL2160158

SMILES CCN(CC)c1ccc(OC)c2nc(c(C)cc12)-c1c(OC)cc(cc1OC)C#N

InChI Key InChIKey=FJJSMVINHZXIPQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394515   

LigandPNGBDBM50394515(CHEMBL2160158)
Affinity DataIC50: 63nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50394515(CHEMBL2160158)
Affinity DataIC50: 132nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed