BDBM50394699 CHEMBL2165631

SMILES Cc1nc(N)sc1CCCNC(=N)NC(=O)CCCCCCCC(=O)NC(=N)NCCCc1sc(N)nc1C

InChI Key InChIKey=FVDUUTISXASABV-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394699   

TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394699(CHEMBL2165631)
Affinity DataEC50:  0.832nMAssay Description:Agonist activity at H2R in spontaneously beating guinea pig right atrium assessed as increase in heart rateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394699(CHEMBL2165631)
Affinity DataEC50:  2.75nMAssay Description:Agonist activity at guinea pig H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394699(CHEMBL2165631)
Affinity DataEC50:  44.7nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed