BDBM50395267 CHEMBL2163608

SMILES Cc1nc2ccc(Nc3c(C)c(N[C@H]4CCCNC4)nc4ccnn34)cc2s1

InChI Key InChIKey=MHAZFQTWVWWROD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395267   

TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395267(CHEMBL2163608)
Affinity DataIC50: 54nMAssay Description:Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395267(CHEMBL2163608)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human MAPKAP-K2 in THP1 cells assessed as inhibition of LPS-induced TNFalpha production incubated 1 hr prior to LPS challenge measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395267(CHEMBL2163608)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CDK2 after 60 mins using [33P]-gamma-ATP by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed